Iran Air Flight 655 was an Iran Air flight from Tehran, Iran, to Dubai, United Arab Emirates, via Bandar Abbas, Iran. On 3 July 1988, at the end of the Iran–Iraq War, the aircraft serving the flight, an Airbus A300 B2-203, was shot down over the Strait of Hormuz by SM-2MR surface-to-air missiles fired from the United States Navy guided missile cruiser USS Vincennes. The aircraft, which had been flying in Iranian airspace over Iran's territorial waters in the Persian Gulf on its usual flight path, was destroyed. All 290 on board, including 66 children and 16 crew, died.[1] Ranking ninth among the deadliest disasters in aviation history, the incident retains the highest death toll of any aviation incident in the Indian Ocean and the highest death toll of any incident involving an Airbus A300 anywhere in the world
http://en.wikipedia.org/wiki/Iran_Air_Flight_655